Saturday, December 28, 2019

Stem Cells Essay - 1034 Words

Mesenchymal stem cells go on to develop into: connective tissue, like adipocytes, stromal cells or tenocytes; muscle tissues, from myoblasts into skeletal, cardiac and smooth muscle types; cartilage, which is created when an osteochondral progenitor cell develops into a chondroblast then a chondrocyte; or bone tissue, which is also developed from an osteochondral progenitor cell, into an osteoblast, then an osteocyte. Hematopoietic stem cells are what create all the different components of blood. They develop into Myeloid Progenitor cells, which then go on to develop into erythroblasts (create erythrocytes, or red blood cells), megakaryoblasts (create megakaryocytes and thrombocytes, which are platelets), and also myeloblasts.†¦show more content†¦It then develops into a polychromatophilic normoblast. At this stage, the cytoplasm begins to create haemoglobin, changing the colour to dark grey-blue, and the chromatin in the nucleus becomes more condensed and knotted. Then, the nuclei completely shrink, forming a orthochromatic normoblast, which then develops into a reticulocyte, an immature red blood cell. Neutrophils Neutrophils are also created from myeloid Progenitor cells, but they then develop into myeloblasts, which create the three types of granulocyte, including neutrophils. Stem Cells in Medicine There are many potential benefits of stem cell research, however, there is a lot more intensive stem cell research that needs to be done to bridge the gap between the promise of stem cells and the actual reality of these uses. There are many areas of medicine where stem cells could be applied, and range from the development of new drugs, possibly for conditions that have no treatments or cures, to cell therapies, where stem cells are used to replace failing or damaged tissue. Together, cardiovascular diseases, such as heart disease, and cancers are the top two causes of death. Regenerative medicine, using stem cells, has the potential to be able to repair heart damage and perhaps improve cancer treatments. Heart Disease At the moment, the aim of heart disease research is to understand in better detail what is involved in heartShow MoreRelatedStem Cells Essay1699 Words   |  7 Pageshas provided us with a hope for these diseases. This essay will address the issue of controversial research in stem cells. This technology offers hope to millions who are victims of a multitude of diseases and disorders. It can be used to regrow limbs, create organs, attack genetic diseases, treat malfunctioning bladders, etc. However, this same technology is also one of the most controversial debates in science today. If you type â€Å"stem cells research† into your Google search bar, you will most likelyRead MoreStem Cells Essay1530 Words   |  7 Pages Stem cells are used every day throughout the United States to help cure diseases and save lives. Stem cells can also be used to study labor defects so that future birth deficiencies can be prevented or reversed. Although as a college student starting a family may not be on your mind yet, it is always beneficial to educate yourself on current trends and new discoveries in stem cell research. Andres Travino and his wife were excited when their son Andy was born ten years ago. Andy prayed and hopedRead MoreStem Cell Essay939 Words   |  4 PagesInduced Pluripotent Stem Cells and their use in Cardiac Regeneration Introduction Myocardial infarction (MI) is the leading causes of mortality and morbidity in the world. Ischemic heart disease, where the oxygen supply to the myocardium is restricted, is a common cause of an MI. Myocardial injury results in loss of cardiomyocytes (cardiac muscle cells) due to apoptosis, and the development of necrotic myocardium, eventually leading to heart failure. The formation of the necrotic myocardium causesRead MoreStem Cell Essay1061 Words   |  5 Pagestreated with the use of embryonic stem cells. Embryonic stem cells are cells derived from the undifferentiated inner mass cells of human embryo. In simpler terms, these cells have the ability of developing into any of the two hundred different cell types in our bodies. Unlike most of the cells in our bodies, such as heart cells or skin cells, which conduct a specific function, a stem cell does not have a specific function until it is specialized (Hogan). A stem cell that is becoming specialized willRead More Stem Cells Es say1128 Words   |  5 PagesEmbryonic Stem Cells â€Å"Embryonic stem cells...are in effect, a human self-repair kit,† (Christopher Reeve, activist – Larry King show). For the advancement of science, stem cells are infinitely valuable, especially when considering all the potential applications in the field of medicine. Stem cell usage is a very controversial topic, because most people think of abortions, cloning, and other negative topics when they hear the term stem cell. However I think those thoughts are because they don’tRead More Stem Cells Essay4600 Words   |  19 Pages Stem cells are a large focus of study in today’s biomedical world. They are cells that exist in an undifferentiated state, and transform into differing tissue types depending on what the cells surrounding them are. The different types of stem cells have the ability to repair many classes of damaged human tissue. However, only one type of stem cell promises to regenerate virtually any class of tissue. This is the highly controversial embryonic stem cell (ESC). Unfortunately, there is a dark sideRead MoreEssay on Stem Cells2760 Words   |  12 Pagesof the most recent advances in stem cell research. 2.nbsp;nbsp;nbsp;nbsp;nbsp;Stem cells should be defined by their ability to renew themselves and diversify into other cell types. 3.nbsp;nbsp;nbsp;nbsp;nbsp;There are several readily accessible sources of stem cells. Strict criteria apply to the use of these sources in medical research. 4.nbsp;nbsp;nbsp;nbsp;nbsp;Stem cells have wide potential application in medicine. quot;Adultquot; stem cells have already been used in the worldsRead MoreStem Cell Research: The Benefits of Stem Cells Essay723 Words   |  3 Pagesextracted the adult stem cells from it and formed an osteoblast, which is a bone forming cell. Six months after the osteoblast was injected, it started forming new bone material which filled the gaps (NIH Stem Cells). Stem cells could be a genius way to treat many diseases and disorders and it should be supported by everyone. Stem cells get their name from the fact that they are basic cells that other cells develop from. They are capable of developing into a wide range of cells. Stem cells could potentiallyRead MoreEssay on Stem Cells2831 Words   |  12 Pages What is a stem cell? nbsp;nbsp;nbsp;nbsp;nbsp;Stem cells have the ability to divide for indefinite periods in culture and to give rise to specialized cells. They are best described in the context of normal human development. Human development begins when a sperm fertilizes an egg and creates a single cell that has the potential to form an entire organism. This fertilized egg is totipotent, meaning that its potential is total. In the first hours after fertilization, this cell divides intoRead More Stem Cell Essay1406 Words   |  6 Pagesothers. Research in the use of stem cells holds limitless possibilities in the medical field. Stem cells are the cells in our bodies that are in their primitive form. These cells have not yet become the type of cell they are destined to be, whether it be nervous tissue or another. However, even though stem cell research is a great new field, its progress is being limited by moral concerns and ethical questions. In order to let medicine reach its full potential, stem cell research should be legalized

Friday, December 20, 2019

Npm And Performance Management Related Literatures

CHAPTER 2 LITERATURE REVIEW â€Å"The NPM Model has focused on delivering market-inspired results and was primarily concerned with efficiency and performance.† (Jarrar and Schiuma, 2007) 2.1. INTRODUCTION Efficiency and performance become two key words for the reform that held by countries in the world. Started in the developed countries, namely United Kingdom and United States under their leader, Margaret Thatcher and Ronald Reagan era, this doctrine then spread to Australia, New Zealand, Europe, Africa, Latin America and Asia. NPM spread and breadth expand globally. Inevitably, this so-called doctrine or paradigm is delivering market-based which one’s country like or dislike diffuse theirs governance in order to well implement it. This movement also inevitably followed as one of the pressure of country’s exogenous factors. The main purpose of this Chapter is to address NPM and Performance Management related literatures. First, the definition of NPM, its objectives and characteristic is clarified in Section 2.2.1. Section 2.3 expands on the explanation of NPM in developing countries. The Chapter progresses with elaborating Performance Management themes in Section 2.4 encompassing definition, essences and challenges, before concluding in Section 2.5. 2.2. NPM AND PERFORMANCE MANAGEMENT ISSUE This section pertains NPM and performance management issues, NPM definition, objectives and elements; how the performance management as main elements of NPM, relevancies ofShow MoreRelatedThe New Public Management ( Npm ) Essay3668 Words   |  15 Pages NPM is a reality. NPM has come to stay and as a conception it will continue to dominate as long as market remains our focus of attention. Inception New public management (NPM) is basically management techniques and practices come from private sector. Now it is a global phenomenon. NPM emphasizes actually on shifting the traditional public administration to new public management. The key elements of NPM including various forms of decentralization within the public sector, the creation of autonomousRead MoreNew Public Management Essay2564 Words   |  11 PagesNew Public Management Public sector reforms adopted in a number of countries such as USA, UK and New Zealand in the last fifteen years and characterised by efficiency units, performance management, contracting out, market type mechanisms, and agency status have come to be known as the New Public Management or NPM. Appearance of the NPM as shifting the paradigm from the old traditional model of administration has been promoted by a remarkable degree of consensus among the political leadership ofRead MoreComparative Analysis of Financial Performance of Public and Private Banks(Case Study)15686 Words   |  63 PagesCOMPARATIVE ANALYSIS OF FINANCIAL PERFORMANCE OF PUBLIC AND PRIVATE BANKS [IN THE CASE OF SELECTED PRIVATE AND PUBLIC BANKS] A SENIOR ESSAY SUBMITTED TO DEPARTMENT OF ACCOUNTING AND FINANCE, IN PARTIAL FULFILLMENT OF THE REQUIREMENT OF BACHELOR OF ARTS DEGREE IN ACCOUNTING AND FINANCE. Prepared by: Ruth Alemayehu ADDIS ABABA UNIVERSITY COLLEGE OF MANAGEMENT, INFORMATICS AND ECONOMIC SCIENCE SCHOOL OF BUSINESS AND PUBLIC ADMINSTRATION DEPARTMENT OF ACCOUNTINGRead MoreThe Role Of Information And Communication Technology On The Performance Of An Organization Essay1973 Words   |  8 PagesVarious numbers of researches have been conducted on the relationships and impact of information and communication technology on the performance of an organization using different techniques of analysis, different countries and sector as well. This chapter presents numerous studies conducted on the subject matter, methods applied, period of coverage, country in which research carried out and the outcome obtained from the study. According to Langdon and Langdon, (2006) IT including computer basedRead MoreThe Impact of the Public Service Reform Programme on Human Resource Development11627 Words   |  47 Pagesgovernment was under performing. The poor performance of the Public Sector was eroding the confidence in the ability of government and state owned enterprises to provide the necessary goods and services. The financial performance of government services and enterprises was economically inefficient just as the operational performance was functionally ineffective. From the early 1970s, Zambia has experienced an outcry against, and criticism of the performance of the Public Sector with most of it beingRead MoreRatio Analysis for the Hospitality Industry- a Cross Sector Compa7085 Words   |  29 PagesJournal of Hospitality Financial Management The Professional Refereed Journal of the Association of Hospitality Financial Management Educators Volume 13 | Issue 1 Article 26 1-1-2005 Ratio Analysis for the Hospitality Industry: A cross Sector Comparison of Financial Trends in the Lodging, Restaurant, Airline and Amusement Sectors Woo Gon Kim Baker Ayoun Recommended Citation Kim, Woo Gon and Ayoun, Baker (2005) Ratio Analysis for the Hospitality Industry: A cross Sector Comparison ofRead MorePerformance-Analysis-of-Top-5-Banks-in-India13126 Words   |  53 PagesTable of content Chapter No. Content List of Tables List of Figures Executive summary Page No 1. Introduction Overview of Banking Objective of study Research methodology Limitation of study 2. Review of literature CAMELS Framework 3. Company profile HDFC BANK SBI AXIS BANK IDBI ICICI BANK 4. 5. Findings and conclusion Bibliography Email: - satishpgoyal@gmail.com PUNE 2010 1|Page List of Tables Table No. 3.1 3.2 3.3 3.4 3.5 3.6 3.7 Table Content Capital Adequacy ratio Earnings Per ShareRead MoreEvaluating Performance Of Commercial Banks10074 Words   |  41 PagesEVALUATING PERFORMANCE OF COMMERCIAL BANKS IN PAKISTAN: â€Å"AN APPLICATION OF CAMEL MODEL† Adnan Zaheer MB-F11-200025 Abdul Karim MB-F11-200023 Abdul Basit Ishaq MB-F11-200017 Sohail Ahmed MB-F11-200028 MBA-20A (2011-2014) ARMY PUBLIC COLLEGE OF MANAGEMENT SCIENCES (APCOMS) KHADIM HUSSAIN ROAD RAWALPINDI AFFILIATED WITH UNIVERSITY OF ENGINEERING AND TECHNOLOGY, TAXILA Acknowledgement Essential and foremost, all praises for the Almighty Allah, the generousRead MoreOrigins And Developments Of Quality Assurance9850 Words   |  40 PagesCH3 Origins and Developments in Quality: QA, TQM in HEI 3.1 Introduction In this chapter the research questions and aims will be addressed through the existing research literature. The chapter discusses educational management and leadership, followed by the literature on Quality Assurance (QA), Total Quality Management (TQM) generally and internationally, including its birth and evolution. The pioneering gurus of TQM are presented. The chapter also discusses QA implementation, followed by commonRead MoreRole of Hr in Organization10279 Words   |  42 PagesFunction in the Modern Public Sector Continuity and Change: The Role of the HR Function in the Modern Public Sector ABSTRACT As the public sector has modernised and sought to become more efficient and cost-effective, the effective and strategic management of people has received increasing prominence and there have been calls for the HR function to play a more strategic role. However, not much is known about whether the role of the HR function has changed substantively. In this paper, we present empirical

Wednesday, December 11, 2019

Managing Diversity in South Africa free essay sample

Introduction In the workplace, diversity in terms of ethnicity, locality, education and skills, age, and gender exist. Managers or employers therefore require innovative ideas to successfully manage employees in the workplace. Diversity management is a relatively new field in the South African business environment. Managing employees and the work environment involves different aspects and is influenced by the internal environment such as in the mission, vision and goals of the organisation as well as the external environment. These aspects include areas where diversity management is important. Managers have various roles to carry out in an organisation in order to provide effective management and deal with the ethical issues. Factors such as changing structures and polices, providing diversity skills training, creating cross functional teams and employee network groups, building relationships, and providing complete managerial support are all factors that contribute towards effective diversity management. A successful diversity management approach must be more accommodating and more capable of promoting the diversity within an organization to bring everyone together and generate effective participation. This means that employees should be regarded as an organized whole that brings meaningful contributions from their social, political, economic, and geographical experiences. 2. Diversity Diversity can be defined as all the ways people differ, that is the different influences to approaching the workplace, communication between employees, satisfaction achieved from performance and identification in the workplace (Daft, Kendrick, amp; Vershinina, 2010). It is a commitment to distinguishing and appreciating the range of characteristics that make individuals unique in an atmosphere that supports and celebrates individual and collective achievement (Tennessee, 2003). Diversity â€Å"represents the multitude of individual differences and similarities that exist among people (Kreitner, 2001). According to Erasmus, diversity applies to all employees and does not only encompass certain differences but rather the entire spectrum of individual differences that make people unique. Therefore diversity cannot be viewed as only racial or religious differentiation but s all differences combined. The notion of diversity describes differences among people as well as similarities. The discipline of managing diversity requires that these two aspects are managed simultaneously. He further suggests that managers are expected to integrate the collective mixture of similarities and differences between workers into the organisation (Erasmus, 2007). Diver sity is more than being politically correct; it is about nurturing a culture that values individuals and their wide assortment of needs and contributions Diversity management is a moderately new field in the South African business environment. Diversity management is ensuring that the necessary factors are in place to provide for and to encourage the continuous development of diversity in the workplace, by incorporating actual and perceived differences to achieve the utmost efficiency (Bandyopadhyay, Hazra, amp; Goswami, 2007). Diversity management can also be defined as the commitment on the part of the organisations to recruit, retain, reward and promote a heterogeneous mix of productive, motivated and committed workers, including people of colour, whites, females and the disabled (Inancevich amp; Gilbert, 2000). The two areas where diversity management are particularly important include: * Workplace diversity. * Global diversity. Workplace diversity refers to the array of distinctions between people in an organisation. Some of the benefits of implementing workplace diversity are; increased adaptability which supplies a variety of solutions to problems in service, sourcing, and allocation of resources, various opinions which include ideas and experiences, and effectiveness in terms of employee performance to attain goals (Greenberg, 2005). Furthermore, enhanced use of employee capacity is encouraged. This involves competitive advantage over other organisations along with prospects and development of employees for retention purposes. Diversity initiatives retain a competitive advantage by improving employee confidence, decreasing interpersonal conflict, facilitating development in new markets and increasing creativity. It also includes the understanding of the marketplace in terms of the changing needs of consumers. Building workplace diversity will also result in the improved extent of understanding in leadership positions that encompasses a variety of skills. Better quality of team problem solving to bring in different perspectives resulting in creativity of ideas and solutions and lastly reduction of costs induce lower turnover, absenteeism and lawsuits (Daft, Kendrick, amp; Vershinina, 2010). Global diversity is more than just demographical factors (such as age, race, gender, ethnicity, disability and sexual orientation), it is about thinking, leadership, skills and style which integrates peoples differences to achieve all the goals planned and is acceptable universally, that is by breaking though barriers through globalisation (Dell, 2011). Globalisation refers to standardisation of products plan and marketing strategy throughout the world by assuming a homogeneous global market of consumers and industrial products (Daft, Kendrick, amp; Vershinina, 2010). A benefit of global diversity is broader services through customer satisfaction and product availability. By managing diversity, managers access a range of skills which the organisation has never had before and thus a broader array of individual strengths, experiences and perspectives. There is also a wider legitimacy and organisational image across a wider audience. Managers however should realise that managing diversity is fairly tough and cannot be implemented immediately. It is instead a long-term strategy in order to correct the imbalances in the workplace. 3. Mission, Vision and Goals A mission is defined as the organisations’ reason for existence. A mission statement is a broadly stated definition of the purpose of the company. Well designed mission statements can enhance employee motivation and organisational performance.

Wednesday, December 4, 2019

Housing Complex Refurbishment Project †MyAssignmenthelp.com

Question: Discuss about the Housing Complex Refurbishment Project. Answer: Introduction The topic that has been chosen for the following project is housing complex refurbishment project. For making it safe for the people to live in the house, the walls will be renovated and the interiors will be redesigned. Some shops are attached on the ground floor and three residential towers (each five storeys) are present in the housing complex. The building needs renovation both in the exterior as well in the interiors as the building is very old. The project was thus proposed by the residents as well as the owner of the building who decided on recruiting contractors for refurbishing the building totally. The project will require several stakeholders and a good project plan is required. A suitable plan for the refurbishment of the house has been developed in the report as well as stakeholder analysis. Communication matrix and stakeholder matrix have been developed simultaneously. Project Plan: Stakeholder Analysis For any project, one of the most important part of it is stakeholder analysis which is utilized to understand the prospective individuals and the role that they will be playing in the project course. For the course of the project, it also helps to define the stakeholders designation. The project stakeholder management has a focal idea that proposes that the supervisors of the project should allocate and appoint duties to the stakeholders which will help them to show their commitment for the project. There lies another stakeholder management issue which shows that as the directors of the project has limited access to some resources of the project, the stakeholders of the project should take charge and manage the budget allocation as well as the entire payment of the project. Project Stakeholders Affected by Internal External Project Process Building Owner Shopkeepers in the Building of the Rental Shops Residents Neighbors Tax Office Municipal Corporation Nearby Clubs Contractor Project Result Residents Shopkeepers in the Building of the Rental Shops Families and friends of the residents Shop clients To determine the roles that will be played by the stakeholders, prioritization and stakeholder identification is necessary. The following matrix utilizes some elements which are external that may affect or may not affect the following project. As all the activities of the stakeholders can be summed up in a normal document table, they are very important aspects for any stakeholder table. The overall benefits and interests of the stakeholders are also determined by the matrix present in the project. Matrix for Stakeholder Prioritization and Identification Stakeholder Stakeholder Stakeholder Stakeholder What is Necessary Owner Residents Contractor Municipal Corporation Power Yes Yes No Yes Interest No Yes Yes No Influence Yes Yes Yes No Impact No Yes Yes No Urgency No Yes No No Legitimacy Yes No No Yes TOTAL Yes 3, No 3 Yes 5, No 1 Yes 3, No 3 Yes 2, No 4 Priority Medium High Medium Low Project Stakeholder Matrix is used to prepare management plan for stakeholder or the total project plan which is made on a particular topic. It is an advanced matrix that is usually used to determine the support strategy as well as the project interests which needs to be implemented during the project course. The stakeholder management needs that the organization wants to consider its position with the stakeholders as the details and corporate heading are set properly. The showcasing methodology needs to be strengthened to as well as the firm destination which would help it to be more successful. Advertisers will be able to take up procedures which would help them to make promoting system that incorporates all the issues and worries of the stakeholders. This can be done by making the advertiser consider who the different stakeholders are and how they are linked with the firm. Project Stakeholder Matrix Stakeholder Interest in Project Priority Support/Mitigation Strategy Building Owner Building Renovation Key Project authorization Residents Room renovation Key Prepare Possible Modifications list Shopkeepers for Attached Shops Shops renovation Key Preparing Possible Modifications list Contractor Renovation Process execution Key Project execution Municipal Corporation Earning money from License Grant Other Grant License in Exchange of Revenue Tax Office Earn Taxes from the Refurbishment Key Against Sufficient Tax, allow Project Residents Friends and Families Newly Furbished House visit Other Offer Ideas Shop customers Refurbished Shops visit Other Offer Ideas Decision Marking Guide of the Project The following table consists of the decision market guide of the project. This will assist managers of the project to assign duties of the project and determine the window of communication for the prospective stakeholders to discuss the solutions regarding the project. Project Decision Making Guide Person When Building Owner When the building becomes not suitable to reside Residents When room refurbishment is necessary Attached Shops shopkeepers When they will require to refurbish the shops Contractor project active, Contract signed Municipal Corporation Project active, submitted Permission request Tax Office During the entire project Friends and Families of residents During execution Shops customers During execution Stakeholder Engagement Matrix The level of determination in executing and managing the project by the stakeholders are analyzed by the following matrix. The matrix can also reveal information about those stakeholders who are trying to resist the project. Unaware Resistant Neutral Supportive Leading Building Owner C D Residents C D Attached Shops shopkeepers C D Contractor C D Municipal Corporation C D Tax Office C D Friends and Families of the residents C D Shops of the customers C D Communication Matrix For determining all the stakeholders that are linked to the project, the communication matrix is necessary. The matrix is useful for allocating all the duties that are necessary for carrying the project to the prospective stakeholders and helps to assort the project who are capable of running the project. The mode of communication which is used by every stakeholder related to the project are mentioned in the communication matrix. For demanding the changes and modifications related to the project, several modes of communication can be used such as verbal, financial reports and documented reports. Stakeholder Learn From Share With Timing Method Owner Building Owner Building Condition Damage / Condition details When Needed Self Inspection Self Residents Room Condition Detailed Condition Weekly Self Inspection Building Owner Shopkeepers for Attached Shops Shop Condition Detailed Condition Weekly Self Inspection Building Owner Contractor Requirements Project Requirements Daily Daily Meetings Lead of the project team Municipal Corporation Permissions and licenses Revenue Biweekly Financial Reports Building Owner Tax Office Taxation Policy Tax Monthly Financial Reports Building Owner Project Meeting Plan For holding a meeting among all the stakeholders for discussing the different topics, a project meeting plan is held in every week. Other topics such as extra requirements and progress of the project are also discussed. In the given table, a project meeting plan has been proposed. Project Team______________ Date_________ Time___________ Place_____________ Topic: Topic Person Time Review Agenda Residents 5 mins Summary Contractor 10 mins Meeting Evaluation Building Owner 5 mins + Buildings Refurbishment Interiors and Exteriors Improvement Expansion opportunity Budget Limitation High Taxation Rarity of Good Contractor Conclusion To conclude the report, for refurbishment of the residential housing complex a suitable project pan has been developed. Several aspects of the project management such as stakeholder management tables and matrices are discussed in the report which have assisted to identify the required stakeholders and allocate them duties related to the particular project. To classify and allocate duties to the stakeholders for achieving the project goals, the matrices have been utilized suitably. Bibliography Boud, D., Cohen, R. and Sampson, J. eds., 2014.Peer learning in higher education: Learning from and with each other. Routledge. Burke, R., 2013. Project management: planning and control techniques.New Jersey, USA. Fleming, Q.W. and Koppelman, J.M., 2016. Earned value project management. Project Management Institute. Kerzner, H., 2013.Project management: a systems approach to planning, scheduling, and controlling. John Wiley Sons. Larson, E.W. and Gray, C., 2013.Project Management: The Managerial Process with MS Project. McGraw-Hill. Nicholas, J.M. and Steyn, H., 2017.Project management for engineering, business and technology. Taylor Francis. Phillips, J., 2013.PMP, Project Management Professional (Certification Study Guides). McGraw-Hill Osborne Media. Schwalbe, K., 2015.Information technology project management. Cengage Learning. Turner, R. (2016).Gower handbook of project management. Routledge. Walker, A., 2015.Project management in construction. John Wiley Sons.